naut-20211102
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): November 2, 2021
NAUTILUS BIOTECHNOLOGY, INC.
(Exact name of registrant as specified in its charter)
Delaware
(State or other jurisdiction
of incorporation)
001-39434
(Commission File Number)
98-1541723
(I.R.S. Employer
Identification No.)
2701 Eastlake Avenue East
Seattle, Washington
(Address of principal executive offices)
98102
(Zip code)
(206) 333-2001
(Registrant’s telephone number, including area code)

425 Pontius Ave N, Ste 202
Seattle, Washington 98109
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
oWritten communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
oSoliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
oPre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
oPre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading Symbol(s)Name of each exchange on which registered
Common Stock, par value $0.0001 per share
NAUT
The Nasdaq Stock Market LLC
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company  x
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.  o



Item 2.02.    Results of Operations and Financial Condition.
On November 2, 2021, Nautilus Biotechnology, Inc. issued a press release reporting its financial results for the quarter ended September 30, 2021. A copy of the press release is furnished herewith as Exhibit 99.1 to this Current Report on Form 8-K.
The information furnished in this Current Report under Item 2.02 and the exhibit attached hereto shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such a filing.
Item 9.01.    Financial Statements and Exhibits.
(d)    Exhibits
Exhibit
Number
Description
104Cover page Interactive Data File (embedded with the Inline XBRL document)
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SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
Dated: November 2, 2021
NAUTILUS BIOTECHNOLOGY, INC.
By:/s/ Sujal Patel
Name:Sujal Patel
Title:Chief Executive Officer

Document
Exhibit 99.1
Nautilus Biotechnology Reports Third Quarter 2021 Financial Results
SEATTLE, WA, November 2, 2021 – Nautilus Biotechnology, Inc. (NASDAQ: NAUT; or “Nautilus”), a company pioneering a single-molecule protein analysis platform for quantifying the proteome, today reported financial results for the third quarter ended September 30, 2021.
Recent Highlights

Initiated a strategic partnership with Abcam, a world leader in the design and production of commercial antibodies, which we expect to accelerate our technology development pipeline and provide access to antibody development expertise that we believe will enhance protein detection in our platform.
Signed our second and third research collaborations, one with a global pharmaceutical company and the other with an investigator at The University of Texas MD Anderson Cancer Center. Both collaborations are expected to utilize the Nautilus platform across a number of projects to investigate proteins and proteoforms of interest.
Shared a manuscript that introduces the theoretical foundation for a fundamentally different approach to proteomics, called Protein Identification by Short-epitope Mapping (PrISM).

“Reflecting on the year thus far, 2021 has been characterized by exciting collaboration agreements, momentum around planned publications, the initiation of strategic partnerships, and our move to new world-class facilities in both San Carlos and Seattle,” said Sujal Patel, CEO of Nautilus. “Our team of scientific and engineering innovators continues to execute and capitalize on a wide range of opportunities. I am very proud of the team and pleased with the progress we are making towards delivering a deeper, richer view of the proteome than ever before possible.”
Third Quarter 2021 Financial Results
Operating expenses were $14.6 million for the third quarter of 2021, a 262% increase from $4.0 million for the three months ended September 30, 2020. The increase in operating expenses was driven primarily by an increase in headcount to support ongoing development of our products as well as the costs associated with being a public company.
Net loss was $14.5 million for the third quarter of 2021, as compared to a net loss of $4.0 million for the corresponding prior year period.
Cash, cash equivalents, and investments were $374.0 million as of September 30, 2021.
Webcast and Conference Call Information
Nautilus will host a conference call to discuss the third quarter 2021 financial results, business developments and outlook before market open on Tuesday, November 2nd, 2021 at 5:30 AM Pacific Time / 8:30 AM Eastern Time. Live audio of the webcast will be available on the “Investors” section of the company website at: www.nautilus.bio.
About Nautilus Biotechnology, Inc.
Based in Seattle, Washington, Nautilus is a development stage life sciences company creating a platform technology for quantifying and unlocking the complexity of the proteome. Nautilus’ mission is to transform the field of proteomics by democratizing access to the proteome and enabling fundamental advancements across human health and medicine. To learn more about Nautilus, visit www.nautilus.bio
Special Note Regarding Forward-Looking Statements
This press release contains forward-looking statements within the meaning of federal securities laws. Forward-looking statements in this press release include, but are not limited to, statements regarding Nautilus’ expectations regarding the company’s business operations, financial performance and results of operations; expectations regarding our collaborations and strategic partnerships, including our expectations with respect to the suitability of the Nautilus product platform to investigate proteins and proteoforms, and the ability of our strategic partnership to accelerate technology development and enhance protein detection; and expectations with respect to the functionality and performance of Nautilus’ product platform, its potential impact on pharmaceutical development and drug discovery. These statements are based on numerous assumptions concerning the development of Nautilus’ products and target markets and involve substantial risks, uncertainties and other factors that may cause actual results to be materially different from the information expressed or implied by these forward-looking statements. Risks and uncertainties that could materially affect the accuracy of Nautilus’ assumptions and its ability to achieve the forward-
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looking statements set forth in this press release include (without limitation) the following: Nautilus’ product platform is not yet commercially available and remains subject to significant scientific and technical development, which is inherently challenging and difficult to predict, particularly with respect to highly novel and complex products such as those being developed by Nautilus. Even if our development efforts are successful, our product platform will require substantial validation of its functionality and utility in life science research. In the course of Nautilus’ scientific and technical development and associated product validation and commercialization, we may experience material delays as a result of unanticipated events. We cannot provide any guarantee or assurance with respect to the outcome of our development, collaboration, and commercialization initiatives or with respect to their associated timelines. For a more detailed description of additional risks and uncertainties facing Nautilus and its development efforts, investors should refer to the information under the caption “Risk Factors” in the Registration Statement on Form S-1 filed with the SEC as well as in our Quarterly Report on Form 10-Q to be filed for the quarter ended September 30, 2021. The forward-looking statements in this press release are as of the date of this press release. Except as otherwise required by applicable law, Nautilus disclaims any duty to update any forward-looking statements. You should, therefore, not rely on these forward-looking statements as representing our views as of any date subsequent to the date of this press release.

Disclosure Information

Nautilus uses filings with the Securities and Exchange Commission, its website (www.nautilus.bio), press releases, public conference calls, public webcasts, and its social media accounts as means of disclosing material non-public information and for complying with Regulation FD. Therefore, Nautilus encourages investors, the media, and others interested in Nautilus to review the information it makes public in these locations, as such information could be deemed to be material information.
Media Contact
Thermal for Nautilus Biotechnology
Kaustuva Das
press@nautilus.bio
Investor Contact
investorrelations@nautilus.bio
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Nautilus Biotechnology, Inc.
Condensed Consolidated Balance Sheets
As of September 30, 2021 and December 31, 2020 (Unaudited)
(in thousands)September 30,
2021
December 31,
2020
Assets
Current assets:
Cash and cash equivalents$190,241 $36,607 
Short-term investments157,104 40,135 
Prepaid expenses and other current assets4,877 917 
Total current assets352,222 77,659 
Property and equipment, net2,046 1,371 
Operating lease right-of-use assets3,685 4,842 
Long-term investments26,627 — 
Other long term assets767 1,139 
Total assets$385,347 $85,011 
Liabilities, Redeemable Convertible Preferred Stock, and Stockholders’ Equity (Deficit)
Current liabilities:
Accounts payable$1,498 $470 
Accrued expenses and other liabilities2,397 1,069 
Current portion of operating lease liability314 1,479 
Total current liabilities4,209 3,018 
Operating lease liability, net of current portion3,291 3,296 
Total liabilities7,500 6,314 
Redeemable convertible preferred stock:
Series Seed redeemable convertible preferred stock— 5,494 
Series A redeemable convertible preferred stock— 27,067 
Series B redeemable convertible preferred stock— 75,857 
Stockholders’ equity (deficit):
Preferred stock— — 
Common stock12 
Additional paid-in capital441,795 600 
Accumulated other comprehensive (loss) income(9)
Accumulated deficit(63,951)(30,325)
Total stockholders’ equity (deficit)377,847 (29,721)
Total liabilities, redeemable convertible preferred stock and stockholders’ equity (deficit)$385,347 $85,011 

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Nautilus Biotechnology, Inc.
Condensed Consolidated Statements of Operations
Three and Nine Months Ended September 30, 2021 and 2020 (Unaudited)
Three Months Ended September 30,Nine Months Ended September 30,
(in thousands, except share and per share amounts)2021202020212020
Operating expenses
Research and development$8,244 $3,317 $19,459 $8,538 
General and administrative6,324 710 14,223 1,886 
Total operating expenses14,568 4,027 33,682 10,424 
Other income (expense), net64 49 56 157 
Net loss$(14,504)$(3,978)$(33,626)$(10,267)
Net loss per share attributable to common stockholders, basic and diluted$(0.12)$(0.13)$(0.47)$(0.36)
Weighted-average shares used in computing net loss per share attributable to common stockholders, basic and diluted124,114,893 29,963,812 71,062,172 28,208,770 

(1)    The weighted-average number of shares of Common Stock outstanding prior to the Business Combination have been retroactively restated to reflect the exchange ratio of approximately 3.6281 established in the Business Combination.

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Nautilus Biotechnology, Inc.
Condensed Consolidated Statements of Operations
Three and Nine Months Ended September 30, 2021 and 2020 (Unaudited)

Nine Months Ended September 30,
(in thousands)20212020
Cash flows from operating activities
Net loss$(33,626)$(10,267)
Adjustments to reconcile net loss to net cash used in operating activities
Depreciation756 516 
Stock-based compensation5,404 119 
Net amortization of premiums on securities190 179 
Amortization of operating lease right-of-use assets1,217 1,232 
Changes in operating assets and liabilities:
Prepaid expenses and other assets(3,860)(318)
Accounts payable887 57 
Accrued expenses and other liabilities1,533 399 
Operating lease liability(1,223)(1,186)
Net cash used in operating activities(28,722)(9,269)
Cash flows from investing activities
Proceeds from sale and maturities of securities 40,000 15,001 
Purchases of securities (183,745)(68,359)
Purchases of property and equipment(1,283)(617)
Net cash used in investing activities(145,028)(53,975)
Cash flows from financing activities
Net proceeds from reverse recapitalization and PIPE financing335,409 — 
Payments of deferred offering costs(8,129)— 
Proceeds from exercise of stock options104 32 
Proceeds from issuance of convertible preferred stock, net of issuance costs— 75,857 
Net cash provided by financing activities327,384 75,889 
Net increase in cash, cash equivalents and restricted cash153,634 12,645 
Cash, cash equivalents and restricted cash at beginning of period37,219 595 
Cash, cash equivalents and restricted cash at end of period$190,853 $13,240 


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